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Take folic acid before pregnancy

If pregnancy is possible, folic acid helps prevent serious defects of the developing brain and spine.

Impact EvidenceAUSPSTF grade A reaffirmation in 2023 and NHS pregnancy guidance reviewed in 2026 EffortQuick win

The number, drawn

400 to 800 micrograms of folic acid daily if pregnancy is possible

Why it matters

The neural tube develops very early, often before someone knows they are pregnant. The USPSTF recommends a daily supplement containing 400 to 800 micrograms for people who could become pregnant. Starting before conception is important because food alone may not provide the recommended amount.

How to do it

  1. If pregnancy is possible, choose a daily supplement in the recommended range.
  2. Start before you conceive, ideally 3 months before, and continue through early pregnancy.
  3. Follow local maternity guidance, such as the NHS advice to continue through the first 12 weeks.
  4. Check prenatal supplement labels to avoid doubling up unintentionally.

Previous neural tube defects, certain medicines or other risk factors may require a different dose prescribed by a clinician.

Do it

Pick the time you have. Anything beats nothing.

Start with the time you have

1 minute

If pregnancy is possible, prepare your question: 'Which folic acid product is right for me, given my medicines and history?'

In real life

  • If pregnancy is possible, ask a pharmacist today which folic acid product is suitable for you.
  • Bring your supplement labels and medicine list to a maternity appointment.
  • Check whether your prenatal already contains folic acid before adding another product.

Watch out for

  • Common mistakeDo not wait until pregnancy is visible: ask about folic acid before conception or as soon as you know.
  • Common mistakeDo not choose a higher dose yourself after a previous affected pregnancy or with certain medicines: ask your clinician.
  • Common mistakeDo not take a supplement containing vitamin A (retinol) in pregnancy: check labels and ask a pharmacist for a pregnancy product.

Trusted guides

Check usSources

Evidence grade
A Meta-analyses of randomised trials, or a major guideline consensus.
Basis
USPSTF grade A reaffirmation in 2023 and NHS pregnancy guidance reviewed in 2026
The number
400 to 800 micrograms of folic acid daily if pregnancy is possible (USPSTF, 2023)
Back to the hundred

General health information, not a diagnosis or an individual treatment plan. Personalization changes the order of suggestions; it does not assess your medical risks. Follow the cautions and consult a qualified clinician when needed.